2017Journal ArticleFLEC measurements

Inflammatory potential of low doses of airborne fungi from fungal infested damp and dry gypsum boards

Knudsen, Sofie M · Gunnarsen, Lars · Madsen, Anne Mette

Building and Environment

In: Building and Environment, vol. 125, pp. 475 - 483, 2017, ISSN: 0360-1323.

Editorial summary

The study compares the inflammatory potential of low-concentration fungal aerosols generated from damp and dried, fungus-infested gypsum boards. The authors generated the aerosols from the test boards with a Particle Field and Laboratory Emission Cell (P-FLEC), collected them by filter or liquid impingement, and assessed them with an HL60 granulocyte assay. Both conditions produced inflammatory responses, with higher activity reported for aerosols from dried boards.

Original editorial summary, not a verbatim abstract, based on the publisher and institutional-repository records plus independent full-text indexing of the apparatus terms.

FLEC use

Direct FLEC measurements

The article's indexed full text contains P-FLEC, Chematec and aerodynamic-particle-sizer apparatus terms, while the reported experiment generated fungal aerosols from damp and dried gypsum boards for biological testing. P-FLEC therefore served as the experimental aerosolization tool applied to the material; the paper's primary contribution was the inflammation study, not method development.

Topics

Dose-responseGranulocyte assayHL60 cellsJ-shapedLow concentrationsTIP